Supplementation of fat grafts with adipose-derived regenerative cells improves long-term graft retention

M Zhu, Z Zhou, Y Chen, R Schreiber… - Annals of plastic …, 2010 - journals.lww.com
Current practice of autologous fat transfer for soft tissue augmentation is limited by poor long-
term graft retention. Adipose-derived regenerative cells (ADRCs) contain several types of
stem and regenerative cells, which may help improve graft retention through multiple
mechanisms. Using a murine fat transplantation model, ADRCs were added to transplanted
fat to test whether ADRCs could improve the long-term retention of the grafts. This study
showed, at both 6 and 9 months after transplantation, ADRCs not only increased graft …

Supplementation of fat grafts with adipose-derived regenerative cells improves long-term graft retention

Z Yingbo, Y Daping - Annals of plastic surgery, 2012 - journals.lww.com
The 1study by Zhu et al1 was designed to test an important hypothesis about whether the
use of adipose-derived regenerative cells (ADRCs) could improve long-term graft retention
in a murine fat transplantation model. Autologous fat transplantation is frequently used for a
variety of cosmetic treatments and difficult reconstructive indications such as involutional
disorders, hemifacial atrophy, sequelae of radiation therapy, or similar problems. However,
the limitations of widespread application of fat transplantation are well known in such difficult …
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Bibliography

  1. Einstein, A., B. Podolsky, and N. Rosen, 1935, “Can quantum-mechanical description of physical reality be considered complete?”, Phys. Rev. 47, 777-780.